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Drug Strength Percentage Calculator

Drug Strength Percentage Calculator

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Drug Strength Percentage Calculator...
Google Custom Search
Drug Strength Percentage Calculator
Calculators to find the percent strength of a drug
(i.e., what % strength is 14 grams in 40 ml of solution.)

Manuel's Web.com is a free site developed by a nurse, that has some great calculators to get you on the right track: The site also includes calculators for finding the active ingredient and drug proportions and much more. This is an excellent resource for all in a health care delivering field!

Go To: Drug Strength Calculator


Need to refresh your math skills?

Go To: Math Tables and Exercises


General Principles

What is pharmacology

Study of drugs
study how drugs are used to cure, treat or prevent disease in humans and animals - pharmacotherapeutics
study how drugs are used to alleviate pain and suffering - pharmacotherapeutics
study of the non-medical use of drugs - drug abuse
study how poisons and environmental toxicants affect humans and animals- toxicology
Another ways to study drugs is to examine what a drug does to the body (Pharmacodynamics) and what the body does to the drug (Pharmacokinetics).

pharmacodynamics
describes the effect of a drugs on the subject to which it is given
biochemical effects
physiological effects
behavioral effects
describes the mechanism(s) of action for the drug

pharmacokinetics
pharmacokinetics describes in qualitative and quantitative terms what happens to an administered drug with the passage of time
drug disposition
absorption
distribution
metabolism
excretion)
experimentally one can measure the concentration of a drug at various times after administration
in general, the intensity of a drug effect is related to its concentration
allows one to make intelligent decisions regarding dose and frequency of drug administration
Drug nomenclature
Chemical name - identifies chemical structure
Generic (official) name - assigned by the U.S. Adopted Name Council
Trade (proprietary) name
assigned by company that developed the drug
during the time company owns patent rights to drug it may license the drug's manufacture and sale by other companies under different trade names
trade names are usually short and catchy and easy to remember but...
multiple trade names may exist for a single drug
trade names for different drugs may sound and/or be spelled so similar that medication errors may occur
a drug can always be recognized by its generic name, regardless of its trade name, since this must appear on the label

Sources of Drug Information
The United States Pharmacopeia (USP) and National Formulary (NF)
describes well-accepted therapeutic agents as to
source
chemistry
physical properties
tests for identity
standards of purity
storage characteristics
therapeutic dose range in humans
general medical uses
legally enforceable standards of drug identity, purity and activity
authoritative and unbiased (but overwhelming, overkill and expensive)
3-volume abbreviated version available - USP DI (Dispensing Information)
Drug Information for the Health Care Professional
Advice for the Patient
Approved Drug Products and Legal Requirements

Physician's Desk Reference (PDR)
only contains information supplied by the pharmaceutical companies
no comparisons among drugs
only lists FDA-approved indications
Drug Facts and Comparisons
Textbooks
Journals
Continuing medical education programs
Drug company representatives
Colleague recommendations
Advertisements

Legal regulation of drugs
Food and Drug Administration (FDA)
Purpose
to approve or reject applications from drug companies to market new drugs
old drugs which fail to meet purity, safety or efficiacy standards may be removed from market
History
1906
Food, Drug and Cosmetic Act
set up federal agency to define purity and quality of drugs (not safety or efficacy)
1938
required accurate labeling of medicinals
assured identity and safety of all ingredients (active and inactive)
1951
allowed FDA to determine which drugs may be dispensed by prescription only and which may be sold "over-the-counter" (OTC)
set the number of refills for prescription drugs
1958
Delaney Ammendment
no drug or food additive may contain any substance which has been shown to be carcinogenic in man or animal (zero tolerance)
1962
manufacturer must demonstrate efficacy as well safety of new drugs
review of drugs introduced between 1938 and 1962
set guidelines for animal and human testing
1972
review of efficacy and safety of OTC drugs

Drug Enforcement Administration (DEA)
purpose of DEA is to establish a balance between legitimate medical needs for a drug while minimizing the availability of the drug for abuse.
regulates drugs acting on the central nervous system that have abuse potential
first set up by Congress in 1914 - subsequent amendments - Harrison Narcotic Act - regulation of opium derivatives, cocaine and marijuana
1970 - Comprehensive Drug Abuse, Prevention and Control Act (Controlled Substances Act) - regulates the manufacture, distribution, dispensing, use and possession of all CNS drugs with abuse potential with the exceptions of alcohol and tobacco (regulated by the ATF, which is part of the Trea$ury Department)
enforced by the DEA of the U.S. Department of Justice
all controlled substances are placed in one of five "schedules " (see table below) depending on their abuse potential and their clinical usefulness
individual states may establish controls that are stricter than those of the DEA (but NOT less stringent) for particular drugs
any preparation containing a controlled substance must be so labeled
a DEA licence is needed to manufacture, prescribe or dispense a controlled substance
all licensees must keep these drugs under lock and key and must keep accurate records and inventories

Units of Measure/Conversions

Length
One inch = 2.54 centimeters
One yard = 0.9144 meters


Volume (fluid)
One teaspoon = 0.16 ounces (or 5 ml)
One tablespoon = 0.5 ounces (or 15 ml or 3 teaspoons)
Four tablespoons = 1/4 cup
One ounce = 30 ml
One cup = 8 ounces (or 240 ml or 16 tbs or 48 tsp)
One pint = 16 ounces
One quart = 32 ounces (or 0.95 liters or 4 cups)
One gallon = 128 ounces (or 3.8 liters or 4 quarts)
One milliliter = 0.0338 ounces


Weight
One gram = 0.035 ounces
One pound = 454 grams
One kilogram (kg) = 2.205 pounds (or 35 ounces)
One grain = 64.799 mg
One microgram (ug) = 0.000001 grams
One ounce = 28 grams


                                                                                                                                                                                                                                                                                                           

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